Table 1 Baseline clinical data of group 1 and group 2 participants
G1: Carriers n = 51 | G2: Overt NOHCM n = 44 | p-value | |
|---|---|---|---|
Baseline features | |||
Age, years, mean (SD) | 39.29 (11.86) | 52.04 (13.32) | < 0.001 |
Female, n (%) | 30.00 (58.82) | 17.00 (33.33) | 0.01 |
BMI, kg/m2, median (IQ) | 23.56 (6.48) | 25.78 (7.15) | 0.004 |
BSA, mean (SD) | 1.85 (0.20) | 1.98 (0.24) | 0.005 |
Sarcomere gene variant, n (%) | 0.581 | ||
MYBPC3 | 31.00 (60.78) | 36.00 (70.59) | |
MYH7 | 12.00 (23.53) | 9.00 (17.65) | |
Other | 8.00 (15.69) | 6.00 (11.76) | |
Family history of sudden death, n(%) | 27.00 (52.94) | 19.00 (37.25) | 0.108 |
Arterial hypertension, n(%) | 5.00 (9.80) | 21.00 (41.18) | < 0.001 |
Diabetes, n (%) | 1.00 (1.96) | 8.00 (15.69) | 0.015 |
Dyslipidemia, n (%) | 4.00 (7.84) | 15.00 (29.41) | 0.005 |
Smoking, n(%) | 5.00 (9.80) | 8.00 (15.69) | 0.353 |
Other cardiac disease, n(%) | 4.00 (7.84) | 8.00 (15.69) | 0.218 |